Therapy is typically directed by a substance use clinic or health care provider and involve supportive care and behavioral and group therapy. Users may encounter problems similar to those experienced by amphetamine and cocaine users, including addiction. Research has shown that animals will self-administer MDMA, an indicator of a drug’s abuse potential.

Potential Acute Adverse Health Effects:

  1. You might still experience some physical effects, like a fast heart beat or insomnia (not being able to sleep), for a few hours after you stop feeling high – especially if you take a lot.
  2. Abuse of MDMA has significantly increased, by 500 percent, from 1993 to 1999.
  3. It targets the serotonin system, a chemical pathway that is affected by other addictive drugs.
  4. Before and during your time on ecstasy, drink one 16-ounce bottle of water for every hour that passes while on the drug.
  5. A similar confusion is found with the link between MDMA and depression.

On the other hand, ecstasy tablets come in different shapes, colors, and sizes. When taken regularly and in higher doses, it can cause long-term effects, which can last for long periods even after the user has stopped taking the drug. Long-term negative effects of the drug include anxiety, depression, and insomnia. Below are the effects of ecstasy on physical health, behavior, psychology, and social life.

What are the effects of MDMA?

As a result, users may become more affectionate than usual, and feel a connection with complete strangers. MDMA functions by increasing production of serotonin, dopamine, and norepinephrine. A synthetic drug is one manufactured in a laboratory environment rather than coming from a natural source. Another survey published in the same year showed that 1 percent of people aged 19 to 28 years in the United States (U.S.) had used the drug within the last month. Do your research, educate yourself, and reach out to local or virtual organizations that can provide support with addiction.


For most people, it is hard to know what to think when considering the possible long term harms of MDMA. One thing that you need to consider, is that a statistically significant effect on memory in a medications for alcohol use disorders study, may reflect a very subtle (but possibly significant) effect on everyday life. Effects being subtle however, may also mean that effects on mental abilities caused by MDMA could go unnoticed.

What are the effects of MDMA use?

The following video from UMass Medical school describes why Molly isn’t the safe alternative to other drugs that some believe it to be. Seek immediate medical attention if the above are experienced following MDMA use. These can lead to liver, kidney, or heart failure, and even death. More serious, and potentially fatal, conditions can arise under certain circumstances. Serotonin also triggers the release of other hormones that can cause feelings of attraction and intimacy.

It’s also important to know that alcohol can interact with MDMA and cause more severe side effects. Drug Enforcement Administration (DEA) has seized drugs marketed as “Molly” only to find out that they were actually harmful substances like methylone and ethylone. For example, MDMA purchased on the street can possibly contain contaminants like methamphetamine, ketamine, dextromethorphan, and even cocaine. Many of these substances can have harmful effects, especially if you don’t know you’re taking them.

Other naturalistic research studies that assess the psychological and cognitive functioning of people who abuse MDMA also find long-lasting impairments. Research studies on nonhuman primates have found decreases in serotinin activity for as long as seven years following MDMA exposure [5]. Some scientists think that humans may be more susceptible to brain damage than are other primates. MDMA clindamycin hcl oral can produce stimulant effects such as an enhanced sense of pleasure and self-confidence and increased energy. Its psychedelic effects include feelings of peacefulness, acceptance, and empathy. MDMA is an illegal drug that acts as both a stimulant and psychedelic, producing an energizing effect, as well as distortions in time and perception and enhanced enjoyment from tactile experiences.

When taken orally, ecstasy normally takes 30 minutes to kick in, but it could take as little as 20 minutes, or it may take over an hour or more. Some other (more dangerous) drugs sold as ecstasy take longer to kick in. Like with pills, drinking too much (including water) can also be dangerous. Users should sip no more than a pint of water or non-alcoholic drink every hour. Research in animals indicates that MDMA is neurotoxic and may affect the brain. Clinical studies suggest that MDMA may increase the risk of long-term or permanent problems with memory and learning.

Its primary effects are in the brain on neurons that use the chemical serotonin to communicate with other neurons. The serotonin system plays an important role in regulating mood, aggression, sexual activity, sleep, and sensitivity to pain. Research and alcohol abuse articles clinical viewpoints vary as to how addictive ecstasy is or even whether it is addictive at all. There are many individuals who report becoming addicted to ecstasy, but the clinical research on the subject is less extensive than with many other drugs.

Although, studies with MDMA users have found impairments in memory and impulsivity, there are other factors which may contribute to this, such as use of other drugs and lack of sleep. Controlling for such things, one particular study found no significant connection between MDMA use and performance on cognitive tests, although this study has received some criticism. Recognizing an addiction to ecstasy can be difficult because the drug lacks obvious withdrawal symptoms and is often used among young people in social settings. Regardless, continued use of ecstasy can lead to psychological and physical dependence. When someone is addicted to ecstasy, they will continue to use the drug despite knowing the consequences. Even when ecstasy is not the only drug causing dependence, it can be a piece of a multi-drug patchwork of addiction.